๐ Health Economics & Outcomes Research (HEOR)
At Calc LLC, we help you demonstrate the value of therapies and interventions with clear, evidence-based insights. Our HEOR service supports pricing, reimbursement, market access, and policy decisions across life sciences and healthcare.

โ What We Offer
๐ Economic Modeling
Cost-effectiveness, cost-utility, and budget impact models (e.g., Markov, partitioned survival) with sensitivity/scenario analyses.
๐งพ Real-World Evidence (RWE)
Evidence gap analyses, NICE/ICER expectations, payer questions, and submission readiness.
๐ Value Communication
AMCP dossiers, payer decks, value narratives, and publication support (abstracts, posters, manuscripts).
๐งช Study Design & Analytics
HEOR protocols, endpoint strategy, analysis plans, and transparent reporting.
๐ Why Choose Calc LLC
๐ง Methodological Rigor
Transparent assumptions, validated models, and reproducible workflows.
๐ค Payer-Ready Storytelling
Clear, concise outputs tailored for HTA bodies and market access teams.
โก Agile & Collaborative
Fast iterations, close partnership with clinical, medical, and commercial stakeholders.
๐ฆ Typical Deliverables
๐ Cost-effectiveness & budget impact models (Excel / R Shiny) + documentation
๐ Technical reports, white papers, and peer-review support
๐ Interactive dashboards and visual summaries
๐งพ AMCP dossiers and payer slide decks
๐ Compliance & Data Ethics: We follow best practices for HIPAA/GDPR, use de-identified data where applicable, and align to good publication practice (GPP).
๐งพ Publications
Maintaining the confidentiality of our private client work is a priority for us. On the other hand, we take pride in the fact that a majority of our academic collaborations have been recognized and published in high-ranking peer-reviewed journals, including The Lancet.
- Active shooters and gun-free zones: emotional versus legal motivations
- Evaluating Disparities in Pathways to Breast Reconstruction
- The Association Between Metabolic Derangement and Wound Complications in Elective Plastic Surgery
- Predicting Academic Performance during Plastic Surgery Residency: Can Step 2 Scores Reliably Replace Step 1?
- Efficacy of Prophylactic Post-Operative Antibiotics in Tissue Expander-Based Breast Reconstruction: A Propensity Score-Matched Analysis
- ASO Visual Abstract: Air or Saline? A Propensity Score-Matched Analysis on the Effect of Tissue Expander Fill on Complications in Immediate Breast Reconstruction
- Defining the Value of Breast Reconstruction Surgeons: Quantifying Clinical Encounter and Operative Volume at an Academic Center
- Health plan enrollment and mortality in the Medicare program
- Analysing user-reported data for enhancement of SmokefreeTXT: a national text message smoking cessation intervention
- Tracking Complications and Unplanned Healthcare Utilization in Aesthetic Surgery: An Analysis of 214,504 Patients Using the TOPS Database
- Mapping Patient Encounters in Breast Cancer Care: An Analysis of 8800 Clinical Encounters Among Patients Undergoing Mastectomy
- The Influence of Age on Complications after Correction of Congenital Breast Deformities: A National Analysis of the Pediatric and Adult NSQIP Datasets
- Air or Saline? A Propensity Score-Matched Analysis on the Effect of Tissue Expander Fill on Complications in Immediate Breast Reconstruction
- Defining Predictors of Future Academic Productivity in Plastic Surgery Residency